STAT3 (Signal Transducer and Activator of Transcription 3) is one of seven of a family of homologous STAT proteins that differentially regulate gene expression. STAT 3 is important in both the development of embryos and many functions in adult organisms. The STAT3 protein is composed of several helix-turn-helix structures and its quaternary structure consists of two STAT3 proteins dimerized with themselves. [1]
Structure
The STAT3 protein is composed of several helix-turn-helix structures and its quaternary structure consists of two STAT3 proteins dimerized with themselves. [2]
Regulation
DNA-Protein Interactions
The by binding to the major groove of the DNA.
Structural highlights
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