Function
Barnase (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium Bacillus amyloliquefaciens. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA.
Relevance
BA structure was used extensively for studying protein folding.
Structural highlights
BA hydrolyzes RNA at GpN sites where the positively charged Lys and Arg coordinate the RNA phosphate group.
3D Structures of Barnase
Updated on 09-November-2015
