ATP-citrate synthase

Function

ATP-citrate synthase (ACS) is part of the citrate cycle. It catalyzes the transformation of ADP, acetyl-CoA and oxaloacetate to ATP, citrate and CoA. ACS is the link between energy metabolism from carbohydrates to the production of fatty acids.

See also Citrate Synthase

Structural highlights

Crystal structures have shown that tartrate and citrate bind to ACS in the same binding site. .