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Isolation Methods
In Strong and Ellington’s 1994 experiment, arginine kinase (AK) was isolated from Limulus polyphemus, the Atlantic horseshoe crab, a marine chelicerate arthropod. They isolated the gene for AK and sequenced the DNA and produced a full genome breakdown of the 1071 nucleotide gene. The 1071 nucleotides translate to a 357 amino acid protein that is extensively similar to AK’s extracted from other organisms. It also provides a similar function to that of creatine kinase, in vertebrates (Strong and Ellington, 1994).
Function
Disease
Relevance
Structural highlights
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