Cellobiohydrolase

From Proteopedia

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spinqualitylabelsall models Glycosylated cellobiohydrolase I catalytic domain complex with cellobiose and Cd+2 ions (yellow) (PDB code 3cel) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Function

Cellobiohydrolase (CBH) is a cellulase which degrades cellulose by hydrolysing the 1,4-β-D-glycosidic bonds. CBH is an exocellulase which cleaves two to four units from the ends of cellulose. There are two types of CBH. CBHI cleaves progressively from the reducing end while CBHII cleaves progressively from the nonreducing end of cellulose.

Structural highlights

The active site of CBH contains Glu-Asp-Glu and is situated at the bottom of a tunnel.

3D structures of cellobiohydrolase

Updated on 29-November-2015