Cell death proteins or Programmed cell death protein or CD279 (CED) are involved in the process of cellular apoptosis. CED-1 is a T cell regulator. CED-1 is expressed on the surface of T cells, B cells and macrophages. It is a membrane protein and acts in suppressing the immune system during pregnancy, tissue allografts, autoimmune diseases and hepatitis. CED-1 has 2 ligands: CED-L1 and CED-L2. Formation of CED-1/CED-L1 complex reduces T cell proliferation at the lymph nodes. For details on CED-4 see CED-4 Apoptosome. (3bik).[1]
