Structural highlights
Function
[NUDT7_ARATH] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8-oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling.[1] [2] [3] [4] [5]
References
- ↑ Ogawa T, Ueda Y, Yoshimura K, Shigeoka S. Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana. J Biol Chem. 2005 Jul 1;280(26):25277-83. Epub 2005 May 5. PMID:15878881 doi:http://dx.doi.org/M503536200
- ↑ Olejnik K, Kraszewska E. Cloning and characterization of an Arabidopsis thaliana Nudix hydrolase homologous to the mammalian GFG protein. Biochim Biophys Acta. 2005 Sep 25;1752(2):133-41. PMID:16154395 doi:http://dx.doi.org/10.1016/j.bbapap.2005.07.021
- ↑ Jambunathan N, Mahalingam R. Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling. Planta. 2006 Jun;224(1):1-11. Epub 2005 Dec 3. PMID:16328543 doi:http://dx.doi.org/10.1007/s00425-005-0183-y
- ↑ Bartsch M, Gobbato E, Bednarek P, Debey S, Schultze JL, Bautor J, Parker JE. Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell. 2006 Apr;18(4):1038-51. Epub 2006 Mar 10. PMID:16531493 doi:http://dx.doi.org/tpc.105.039982
- ↑ Ge X, Li GJ, Wang SB, Zhu H, Zhu T, Wang X, Xia Y. AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol. 2007 Sep;145(1):204-15. Epub 2007 Jul 27. PMID:17660350 doi:http://dx.doi.org/pp.107.103374
