1psr
From Proteopedia
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HUMAN PSORIASIN (S100A7)
Overview
BACKGROUND: The S100 family consists of small acidic proteins, belonging, to the EF-hand class of calcium-binding proteins. They are primarily, regulatory proteins, involved in cell growth, cell structure regulation, and signal transduction. Psoriasin (S100A7) is an 11.7 kDa protein that is, highly upregulated in the epidermis of patients suffering from the chronic, skin disease psoriasis. Although its exact function is not known, psoriasin is believed to participate in the biochemical response which, follows transient changes in the cellular Ca2+ concentration. RESULTS: The, three-dimensional structure of holmium-substituted psoriasin has been, determined by multiple anomalous wavelength dispersion (MAD) phasing and, refined to atomic resolution (1.05 A). The structure represents the ... [(full description)]
About this Structure
1PSR is a [Single protein] structure of sequence from [Homo sapiens] with HO as [ligand]. Full crystallographic information is available from [OCA].
Reference
EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing., Brodersen DE, Etzerodt M, Madsen P, Celis JE, Thogersen HC, Nyborg J, Kjeldgaard M, Structure. 1998 Apr 15;6(4):477-89. PMID:9562557
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