4rl5

Structural highlights

Function

[E70A1_ARATH] Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall. Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat. Involved in the recycling and localization of auxin efflux carriers PIN1 and PIN2, and thus in polar auxin transport regulation. Functions in vesicle trafficking in tracheary elements to regulate patterned secondary cell wall thickening.^{[1] [2] [3] [4] [5]}

References

1. ↑ Synek L, Schlager N, Elias M, Quentin M, Hauser MT, Zarsky V. AtEXO70A1, a member of a family of putative exocyst subunits specifically expanded in land plants, is important for polar growth and plant development. Plant J. 2006 Oct;48(1):54-72. Epub 2006 Aug 31. PMID:16942608 doi:http://dx.doi.org/10.1111/j.1365-313X.2006.02854.x
2. ↑ Kulich I, Cole R, Drdova E, Cvrckova F, Soukup A, Fowler J, Zarsky V. Arabidopsis exocyst subunits SEC8 and EXO70A1 and exocyst interactor ROH1 are involved in the localized deposition of seed coat pectin. New Phytol. 2010 Oct;188(2):615-25. doi: 10.1111/j.1469-8137.2010.03372.x. Epub, 2010 Jul 2. PMID:20618910 doi:http://dx.doi.org/10.1111/j.1469-8137.2010.03372.x
3. ↑ Fendrych M, Synek L, Pecenkova T, Toupalova H, Cole R, Drdova E, Nebesarova J, Sedinova M, Hala M, Fowler JE, Zarsky V. The Arabidopsis exocyst complex is involved in cytokinesis and cell plate maturation. Plant Cell. 2010 Sep;22(9):3053-65. doi: 10.1105/tpc.110.074351. Epub 2010 Sep, 24. PMID:20870962 doi:http://dx.doi.org/10.1105/tpc.110.074351
4. ↑ Drdova EJ, Synek L, Pecenkova T, Hala M, Kulich I, Fowler JE, Murphy AS, Zarsky V. The exocyst complex contributes to PIN auxin efflux carrier recycling and polar auxin transport in Arabidopsis. Plant J. 2013 Mar;73(5):709-19. doi: 10.1111/tpj.12074. Epub 2013 Jan 10. PMID:23163883 doi:http://dx.doi.org/10.1111/tpj.12074
5. ↑ Li S, Chen M, Yu D, Ren S, Sun S, Liu L, Ketelaar T, Emons AM, Liu CM. EXO70A1-mediated vesicle trafficking is critical for tracheary element development in Arabidopsis. Plant Cell. 2013 May;25(5):1774-86. doi: 10.1105/tpc.113.112144. Epub 2013 May, 24. PMID:23709627 doi:http://dx.doi.org/10.1105/tpc.113.112144