Sandbox T1SS T2SS

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Contents 1 Description/Function 2 Structure 3 Energetics 4 References 4.1 Authors

Description/Function

The Type II secretion system (T2SS) is a secretion pathway found in Gram-negative bacteria. Following transport of a protein from the cytoplasm to the periplasm via the Sec or Tat pathway, the T2SS transports proteins from the periplasm to the extracellular environment^[1].

Structure

Each T2SS is made of many general secretory proteins (GSPs). 12-15 GSPs compose one secretory system, and they are often from the same gene cluster and found on the same operon ^[2]. The T2SS consists of four core components: an outer membrane complex, an inner membrane complex, an ATPase on the cytoplamsic side, and a pseudopilus.

Energetics

References

1. ↑ Saier, Milton H. “Protein Secretion Systems in Gram-Negative Bacteria.” 2006. Microbe 1: 414-419.
2. ↑ Cianciotto, Nicholas. “Type II secretion: a protein secretion system for all seasons.” 2005. Trends in Microbiology 13: 581-588.

Authors