Core-binding factor

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Human CBFα runt domain (grey and pink) complex with CBFβ heterodimerization domain (green and yellow) and DNA (PDB code 1h9d)

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3D Structures of core-binding factor

Updated on 14-December-2015


References

  1. Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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