Flippases are the homodimeric transmembrane proteins located in the membrane. It helps phospholipid to transport from inner face to outer face of the cell membrane. It is composed with alpha-helix and beta sheets. The main three structural features of each monomer are an external helix, a belt of positively charged amino acids, and a binding site for an ATP molecule.
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Function
Flippases flip the lipid from cytoplasmic side to periplasmic side.
Disease
Relevance
Structural highlights
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