Dihydrolipoamide acetyltransferase

From Proteopedia

spinqualitylabelsall models Dihydrolipoamide acetyltransferase (blue) complex with E1 subunit α (pink, gold) and E1 subunit β (cyan, indianred) (PDB entry 3duf) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image is part of the pyruvate dehydrogenase complex together with pyruvate dehydrogenase (E1) and dihydrolipoyl dehydrogenase (E3). The complex decarboxylates pyruvate thus linking the glycolysis to the citric acid cycle. DLAT catalyzes the transfer of acetyl group to CoA.[1]

3D structures of dihydrolipoamide acetyltransferase

Updated on 29-December-2015

References

1. ↑ Lai WL, Chou LY, Ting CY, Kirby R, Tsai YC, Wang AH, Liaw SH. The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation. J Biol Chem. 2004 Apr 2;279(14):13962-7. Epub 2004 Jan 21. PMID:14736882 doi:http://dx.doi.org/10.1074/jbc.M308849200