This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


DnaC helicase loader

From Proteopedia

Revision as of 12:41, 3 January 2016 by Michal Harel (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 2vye

DnaC helicase loader (DnaC) transfers helicase to replication origins. The helicase loaders belong to two classes. The ‘ring breakers’ break the hexameric helicase to allow the DNA to pass through. The ‘ring makers’ assemble the helicase monomers to hexamers around the DNA.[1]

For the theoretical model structure of E. coli DnaC see Structure of E. coli DnaC helicase loader.

3D Structures of DnaC helicase loader

Updated on 03-January-2016

3ec2 – AaDnaC – Aquifex aeolicus
3ecc – AaDnaC + ADP-BeF3
2vye – GkDnaC + DNA – Geobacillus kaustophilus
2vyf – GkDnaC

References

  1. ↑ Arias-Palomo E, O'Shea VL, Hood IV, Berger JM. The bacterial DnaC helicase loader is a DnaB ring breaker. Cell. 2013 Apr 11;153(2):438-48. doi: 10.1016/j.cell.2013.03.006. Epub 2013 Apr, 4. PMID:23562643 doi:http://dx.doi.org/10.1016/j.cell.2013.03.006

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Eric Martz

Retrieved from "http://52.214.119.220/wiki/index.php/DnaC_helicase_loader"
Personal tools