This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Met repressor

From Proteopedia

Revision as of 07:12, 11 January 2016 by Michal Harel (Talk | contribs)
Jump to: navigation, search
Image:1mjo.png
EcMR (mutant) complex with corepressor SAM and DNA 2eyi

Template:STRUCTURE 1mjo












Met repressor (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The corepressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis. Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis. For additional details see
Taylor met rpressor
Joe Granger Methionine Repressor: Escherichia coli.

3D Structures of Met repressor

Updated on 11-January-2016

1cmb – EcMR – Escherichia coli
1mjk – EcMR (mutant)
1cma – EcMR + DNA
1mjm – EcMR (mutant) + DNA
1cmc – EcMR + SAM
1mjl, 1mjp – EcMR (mutant) + SAM
1mj2, 1mjo, 1mjq – EcMR (mutant) + SAM + DNA

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Met_repressor"
Personal tools