Factor XIII

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Template:STRUCTURE 1ggt

Factor XIII (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide[1].

3D Structures of Factor XIII

Updated on 20-January-2016

1ggt – hFXIII - human
1ex0 – hFXIII zymogen (mutant)
1fie – hFXIII subunit A
1f13 - hFXIII zymogen subunit A dimer
4kty - hFXIII subunit A + peptide-like ligand
1ggy, 1qrk, 1ggu, 1evu – hFXIII + ion
1de7 – hFXIII activation peptide + α-thrombin

References

  1. ↑ Laki K, Lorand L. On the Solubility of Fibrin Clots. Science. 1948 Sep 10;108(2802):280. PMID:17842715 doi:http://dx.doi.org/10.1126/science.108.2802.280

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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