1d59

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PDB ID 1d59

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, resolution 2.300Å
Ligands: ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA


Overview

The sequence d(GGGGTTTTGGGG) from the 3' overhang of the Oxytricha telomere has been crystallized and its three-dimensional structure solved to 2.5 A resolution. The oligonucleotide forms hairpins, two of which join to make a four-stranded helical structure with the loops containing four thymine residues at either end. The guanine residues are held together by cyclic hydrogen bonding and an ion is located in the centre. The four guanine residues in each segment have a glycosyl conformation that alternates between anti and syn. There are two four-stranded molecules in the asymmetric unit showing that the structure has some intrinsic flexibility.

About this Structure

1D59 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure of four-stranded Oxytricha telomeric DNA., Kang C, Zhang X, Ratliff R, Moyzis R, Rich A, Nature. 1992 Mar 12;356(6365):126-31. PMID:1545863

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