Structural highlights
3lxy is a 1 chain structure with sequence from "bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , |
| Gene: | pdxA, YPO0493, y3682, YP_3686 ("Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900) |
| Activity: | 4-hydroxythreonine-4-phosphate dehydrogenase, with EC number 1.1.1.262 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum |
Function
[PDXA_YERPE] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity).
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
