Structural highlights
3bab is a 1 chain structure with sequence from "enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 3ba8, 3ba9, 3baa |
| Gene: | ligA ("Enterococcus proteiformis" Thiercelin and Jouhaud 1903) |
| Activity: | DNA ligase (NAD(+)), with EC number 6.5.1.2 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum |
Function
[DNLJ_ENTFA] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity).
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
See Also
