2cof

Structural highlights

Function

[AF1L2_HUMAN] May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Xu J, Bai XH, Lodyga M, Han B, Xiao H, Keshavjee S, Hu J, Zhang H, Yang BB, Liu M. XB130, a novel adaptor protein for signal transduction. J Biol Chem. 2007 Jun 1;282(22):16401-12. Epub 2007 Apr 5. PMID:17412687 doi:http://dx.doi.org/10.1074/jbc.M701684200