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NADH peroxidase

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Revision as of 08:40, 16 February 2016 by Michal Harel (Talk | contribs)
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Template:STRUCTURE 2npx

NADH peroxidase (NPO) catalyzes the conversion of NADH to NAD+ using hydrogen peroxide. See NAD. NPO eliminates the potentially toxic hydrogen peroxide and defends the cell against H2O2-mediated oxidative stress. NPO provides an additional pathway for regeneration of NAD+ which is essential to the fermentative metabolism. FAD is the cofactor in this reaction.

3D structures of NADH peroxidase

1npx, 1joa – EfNPO – Enterococcus faecalis
2npx – EfNPO + NAD
1nhp, 1nhq, 1nhr, 1nhs, 1f8w – EfNPO (mutant)

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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