Factor VIII

From Proteopedia

Revision as of 13:12, 16 February 2016 by Alexander Berchansky (Talk | contribs)

(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)

Glycosylated human Factor VIII. Residues 19-760 (cyan), 1582-2351 (magenta) complex with Ca+2 (green) and Cu+2 (orange) ions (PDB code 2r7e)

Drag the structure with the mouse to rotate

3D Structures of Factor VIII

Updated on 16-February-2016

2r7e, 3cdz, 3j2q, 4bdv – hFVIII – human
3hnb, 3hny, 3hob – hFVIII light chain C2 domain
1d7p - hFVIII light chain C2 domain (mutant)
1cfg, 1fac - hFVIII light chain C2 domain membrane-binding peptide - NMR
1iqd - hFVIII light chain C2 domain (mutant) + monoclonal Fab
4ki5 - mFVIII light chain C2 domain + monoclonal Fab – mouse
3j2s - hFVIII light chain
4mo3 - FVIII light chain C2 domain – pig

References

↑ White GC 2nd, Shoemaker CB. Factor VIII gene and hemophilia A. Blood. 1989 Jan;73(1):1-12. PMID:2491949
↑ Shen BW, Spiegel PC, Chang CH, Huh JW, Lee JS, Kim J, Kim YH, Stoddard BL. The tertiary structure and domain organization of coagulation factor VIII. Blood. 2008 Feb 1;111(3):1240-7. Epub 2007 Oct 26. PMID:17965321 doi:10.1182/blood-2007-08-109918