Fumarase C is the stable fumarase found in E. coli acting as a "non-iron-containing enzyme" found in eukaryotic cells. Fumarase is a vital enzyme in eukaryotic cells because it has the ability to catalyze dehydration and hydration reactions between L-malate and fumarate,[1] a reaction found in the Krebs Cycle.
Active Site Debate
| Header C1
| Header C2
| Header C3
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| R1C1
| R1C2
| R1C3
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| R2C1
| R2C2
| R2C3
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Structure of Active Site
References
- ↑ Weaver T, Lees M, Banaszak L. Mutations of fumarase that distinguish between the active site and a nearby dicarboxylic acid binding site. Protein Sci. 1997 Apr;6(4):834-42. PMID:9098893
