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Formate dehydrogenase

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Revision as of 10:44, 2 March 2016 by Michal Harel (Talk | contribs)

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Template:STRUCTURE 2nad Formate dehydrogenase (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either NAD+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe₄S₄ center and then to cytochrome. The Mo-dependent FDH-H from E. coli contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe₄S₄^[1].