4zwr

Structural highlights

Function

[UVSY_BPT4] Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA.^{[1] [2]}

References

1. ↑ Pant K, Shokri L, Karpel RL, Morrical SW, Williams MC. Modulation of T4 gene 32 protein DNA binding activity by the recombination mediator protein UvsY. J Mol Biol. 2008 Jul 25;380(5):799-811. doi: 10.1016/j.jmb.2008.05.039. Epub 2008, May 24. PMID:18565541 doi:http://dx.doi.org/10.1016/j.jmb.2008.05.039
2. ↑ Xu H, Beernink HT, Morrical SW. DNA-binding properties of T4 UvsY recombination mediator protein: polynucleotide wrapping promotes high-affinity binding to single-stranded DNA. Nucleic Acids Res. 2010 Aug;38(14):4821-33. doi: 10.1093/nar/gkq219. Epub 2010, Apr 5. PMID:20371513 doi:http://dx.doi.org/10.1093/nar/gkq219