Glutamate racemase

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spinqualitylabelsall models Structure of glutamate racemase dimer complex with D-glutamate (PDB entry 2jfq) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Glutamate racemase (GR) catalyzes the racemization of L-glutamate to D-glutamate. GR plays a major role in bacterial cell wall biosynthesis and moonlights as gyrase inhibitor[1]. Relevance GR inhibition is used as anti-bacterial target.

3D Structures of glutamate racemase

Updated on 08-March-2016

References

1. ↑ Sengupta S, Ghosh S, Nagaraja V. Moonlighting function of glutamate racemase from Mycobacterium tuberculosis: racemization and DNA gyrase inhibition are two independent activities of the enzyme. Microbiology. 2008 Sep;154(Pt 9):2796-803. doi: 10.1099/mic.0.2008/020933-0. PMID:18757813 doi:http://dx.doi.org/10.1099/mic.0.2008/020933-0