5f2z

Structural highlights

Function

[ACYLT_MYCS2] Catalyzes the acylation to the position 6 of the alpha-1,2-linked mannose residue of the phosphatidyl-myo-inositol dimannoside (PIM2) or monomannoside (PIM1).^[1]

References

1. ↑ Kordulakova J, Gilleron M, Puzo G, Brennan PJ, Gicquel B, Mikusova K, Jackson M. Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species. J Biol Chem. 2003 Sep 19;278(38):36285-95. Epub 2003 Jul 8. PMID:12851411 doi:http://dx.doi.org/10.1074/jbc.M303639200