Hemolysin

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Template:STRUCTURE 7ahl

Hemolysin (HL) is exotoxin from bacteria which causes lysis of red blood cells[1]. Hemolysin from the bacterium Clostridium are called alpha-toxin (AT). AT is a zinc metalloenzyme and binds to the membrane in the presence of calcium. It acts as a phospholipase C.

See details for α-hemolysin in Pore forming toxin, α-hemolysin. See details of hemolysin E in Molecular Playground/ClyA.

For toxins in Proteopdia see Toxins.

3D Structures of hemolysin

Updated on 21-March-2016

A full page in Proteopedia exploring 7ahl is found here.

References

  1. ↑ Mestre MB, Fader CM, Sola C, Colombo MI. Alpha-hemolysin is required for the activation of the autophagic pathway in Staphylococcus aureus-infected cells. Autophagy. 2010 Jan;6(1):110-25. PMID:20110774

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Mark Hoelzer, Wayne Decatur, Alexander Berchansky

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