Histone
From Proteopedia
Histones (H) are the major protein components of chromatin which help to pack the DNA in the nucleosomes. H2A, H2B, H3 and H4 are core histones while H1 and H5 are linker histones[1]. The nucleosome is the repeated unit of the chromatin consisting of 8 histone molecules wrapped by ca. 200 base pairs of DNA[2].
- For the hyperthermophilic histones see Archaeal Histones.
- For nucleosome structure see User:Eric Martz/Nucleosomes, Nucleosome structure and Nucleosomes.
3D Structures of histone
Updated on 22-March-2016
References
- ↑ Marino-Ramirez L, Kann MG, Shoemaker BA, Landsman D. Histone structure and nucleosome stability. Expert Rev Proteomics. 2005 Oct;2(5):719-29. PMID:16209651 doi:http://dx.doi.org/10.1586/14789450.2.5.719
- ↑ Kornberg RD. Chromatin structure: a repeating unit of histones and DNA. Science. 1974 May 24;184(4139):868-71. PMID:4825889
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