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Lysophosphatidic Acid
Lysophosphatidic acid (LPA) is a phospholipid signalling molecule that is present in nearly all cells, tissues, and fluids of the body. LPA interacts with at least six G protein coupled receptors LPA1-LPA6.
Function
Human lysophosphatidic acid receptor 1 is coupled to a heterotrimeric G protein.
Structure
Similarities to S1P
Clinical Relevance
Infertility
Fibrosis
Cancer
Endocannabinoids
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