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Neuroligin

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Revision as of 07:49, 9 May 2016 by Michal Harel (Talk | contribs)
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Image:3be8a.png
Crystal Structure of human Neuroligin 3be8

Template:STRUCTURE 3b3q











Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. In humans the NLGN family contains 4 to 5 members that are numbered 1, 2, 3, 4X and 5 or 4Y[1].

See Neurodevelopmental Disorders

Neuroligin-Neurexin Interaction

3D Structures of Neuroligin

09-May-2016

References

  1. ↑ Fabrichny IP, Leone P, Sulzenbacher G, Comoletti D, Miller MT, Taylor P, Bourne Y, Marchot P. Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion. Neuron. 2007 Dec 20;56(6):979-91. PMID:18093521 doi:10.1016/j.neuron.2007.11.013
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