Structural highlights
Function
[G3PC1_ARATH] Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism. Involved in response to oxidative stress by mediating plant responses to abscisic acid (ABA) and water deficits through the activation of PLDDELTA and production of phosphatidic acid (PA), a multifunctional stress signaling lipid in plants. Required for full fertility. Binds DNA in vitro.[1] [2]
References
- ↑ Rius SP, Casati P, Iglesias AA, Gomez-Casati DF. Characterization of Arabidopsis lines deficient in GAPC-1, a cytosolic NAD-dependent glyceraldehyde-3-phosphate dehydrogenase. Plant Physiol. 2008 Nov;148(3):1655-67. doi: 10.1104/pp.108.128769. Epub 2008 Sep, 26. PMID:18820081 doi:http://dx.doi.org/10.1104/pp.108.128769
- ↑ Guo L, Devaiah SP, Narasimhan R, Pan X, Zhang Y, Zhang W, Wang X. Cytosolic glyceraldehyde-3-phosphate dehydrogenases interact with phospholipase Ddelta to transduce hydrogen peroxide signals in the Arabidopsis response to stress. Plant Cell. 2012 May;24(5):2200-12. doi: 10.1105/tpc.111.094946. Epub 2012 May, 15. PMID:22589465 doi:http://dx.doi.org/10.1105/tpc.111.094946
