Structural highlights
, pdb structure 3fhi[1], is shown with the catalytic unit's small lobe in gray and large lobe in tan, and the regulatory unit in light blue.
There is . Here the residues which interact with the regulatory unit R are represent with halos and ball-and-stick. The residues from the catalytic unit's exon 1 are labelled by residue index. Note that the last three residues from exon 1 (residues # 13-15) are the only amino acids from the first exon of the catalytic unit that were included in this crystal structure.
These three residues are also - a second regulator/inhibitor of 'C', as well.
This is also obvious from the pdb structure for the , 1atp[2].