Nucleoprotein

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Nucleoproteins (NP) are proteins associated with DNA or RNA[1]. NPs which contain RNA are called ribonucleoproteins (RNPs). The NP RNA-recognition motif is named RRM. The small nuclear ribonucleoproteins (snRNPs) are RNA-protein complexes which form part of the spliceosome[2]. The heterogenous nuclear ribonucleoproteins (hnRNP) are RNA-protein complexes which associates with the splicing apparatus and prevent the folding of pre-mRNA.
For details on heterogenous nuclear ribonucleoproteins see HnRNP A1.
For homology model and multiple sequence alignment see User:Michael Strong/H1N1/NP and User:Michael Strong/H1N1/NP/MSA.

3D Structures of Nucleoprotein

Updated on 06-June-2016

References

  1. ↑ Echols H. Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination. J Biol Chem. 1990 Sep 5;265(25):14697-700. PMID:2203758
  2. ↑ Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol. 2004 May;14(5):226-32. PMID:15130578 doi:http://dx.doi.org/10.1016/j.tcb.2004.03.010

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Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman

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