5dtm, resolution 2.20Å
[DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
OCA
Categories: Histone-lysine N-methyltransferase | Be, C | Moebitz, H | Scheufler, C | Stauffer, F | Complex | Inhibitor | Methyltransferase | Transferase