Plasminogen activator

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Plasminogen activator (PLA) is a serine protease which converts plasminogen to plasmin. TPA structure contains heavy and light chains (HC, LC). PLA is inhibited by PLA inhibitor 1 and 2.

  • Tissue PLA (TPA) which is involved in breakdown of blood clots and urokinase-type PLA Urokinase.

3D structures of plasminogen activator

Updated on 04-July-2016


References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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