Structural highlights
5ieg is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , , , |
| Related: | 5f0e, 5hjo, 5hjr, 5h9o, 5ied, 5iee, 5ief |
| Activity: | Hydrolase, with EC number 3.2.1.84 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[GANAB_MOUSE] Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. [GLU2B_MOUSE] Regulatory subunit of glucosidase II.[1]
References
- ↑ Arendt CW, Ostergaard HL. Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II. J Biol Chem. 1997 May 16;272(20):13117-25. PMID:9148925
