Structural highlights
5jx1 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Related: | 5jv3, 5jvm, 5jvp, 5jvr, 5jvs, 5jvu |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[KIF3A_MOUSE] Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation.[1]
References
- ↑ Choi YH, Suzuki A, Hajarnis S, Ma Z, Chapin HC, Caplan MJ, Pontoglio M, Somlo S, Igarashi P. Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10679-84. doi:, 10.1073/pnas.1016214108. Epub 2011 Jun 13. PMID:21670265 doi:http://dx.doi.org/10.1073/pnas.1016214108
