Structural highlights
4iqf is a 4 chain structure with sequence from "bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946. This structure supersedes the now removed PDB entry 3rfo. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , |
| NonStd Res: | |
| Gene: | BAS3717, BA_4004, fmt, GBAA_4004 ("Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946) |
| Activity: | Methionyl-tRNA formyltransferase, with EC number 2.1.2.9 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[FMT_BACAN] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP.[HAMAP-Rule:MF_00182]
