Structural highlights
3p6b is a 2 chain structure with sequence from Atcc 27405. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Ligands: | , , , |
| Related: | 3k4z |
| Gene: | celK (ATCC 27405) |
| Activity: | Cellulose 1,4-beta-cellobiosidase (non-reducing end), with EC number 3.2.1.91 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
Here, a 2.0 A resolution X-ray structure of Clostridium thermocellum cellulase K family 4 carbohydrate-binding module (CelK CBM4) is reported. The resulting structure was refined to an R factor of 0.212 and an R(free) of 0.274. Structural analysis shows that this new structure is very similar to the previously solved structure of C. thermocellum CbhA CBM4. Most importantly, these data support the previously proposed notion of an extended binding pocket using a novel tryptophan-containing loop that may be highly conserved in clostridial CBM4 proteins.
Structure of CBM4 from Clostridium thermocellum cellulase K.,Alahuhta M, Luo Y, Ding SY, Himmel ME, Lunin VV Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt, 5):527-30. Epub 2011 Apr 20. PMID:21543854[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Alahuhta M, Luo Y, Ding SY, Himmel ME, Lunin VV. Structure of CBM4 from Clostridium thermocellum cellulase K. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt, 5):527-30. Epub 2011 Apr 20. PMID:21543854 doi:10.1107/S1744309111003307
