Structural highlights
Function
[3DHQ_CANAL] Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.[HAMAP-Rule:MF_03136]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The combination of transmission electron microscopy with X-ray diffraction data is usually limited to relatively large particles. Here, the approach is continued one step further by utilizing negative staining, a technique that is of wider applicability than cryo-electron microscopy, to produce models of medium-size proteins suitable for molecular replacement. The technique was used to solve the crystal structure of the dodecameric type II dehydroquinase enzyme from Candida albicans (approximately 190 kDa) and that of the orthologous Streptomyces coelicolor protein.
Macromolecular crystal data phased by negative-stained electron-microscopy reconstructions.,Trapani S, Schoehn G, Navaza J, Abergel C Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):514-21. Epub 2010, Apr 21. PMID:20445226[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Trapani S, Schoehn G, Navaza J, Abergel C. Macromolecular crystal data phased by negative-stained electron-microscopy reconstructions. Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):514-21. Epub 2010, Apr 21. PMID:20445226 doi:10.1107/S0907444910002763
