| Structural highlights
3ag7 is a 1 chain structure with sequence from Arath. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| | Related: | 1nz6, 2qwo, 2qwr, 2qwp, 2qwq, 2qwn |
| Gene: | At1g75100, F9E10.5, JAC1 (ARATH) |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[JAC1_ARATH] Required for chloroplast photorelocation movement; chloroplast accumulation upon low blue light and for chloroplast movement to the bottom of cells in darkness, by modulating chloroplast actin (Cp-actin) filaments distribution, appearance and disappearance. May mediate a slight resistance to aluminum in root hair cells.[1] [2] [3] [4]
Publication Abstract from PubMed
An auxilin-like J-domain-containing protein, JAC1, is necessary for chloroplast movement in Arabidopsis thaliana, to capture photosynthetic light efficiently under weak light conditions. Here, we performed crystallographic and functional analyses of the J-domain of JAC1. The crystal structure of the J-domain is quite similar to that of bovine auxilin, and possesses a similar positively charged surface, which probably forms the interface with the Hsp70 chaperone. The mutation of the highly conserved HPD motif of the JAC1 J-domain abrogated the chloroplast photorelocation response. These results suggest that the requirement of JAC1 in chloroplast photorelocation movement is attributable to the J-domain's cochaperone activity.
Crystallographic and functional analyses of J-domain of JAC1 essential for chloroplast photorelocation movement in Arabidopsis thaliana.,Takano A, Suetsugu N, Wada M, Kohda D Plant Cell Physiol. 2010 Aug;51(8):1372-6. Epub 2010 Jun 20. PMID:20562448[5]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Suetsugu N, Kagawa T, Wada M. An auxilin-like J-domain protein, JAC1, regulates phototropin-mediated chloroplast movement in Arabidopsis. Plant Physiol. 2005 Sep;139(1):151-62. Epub 2005 Aug 19. PMID:16113208 doi:http://dx.doi.org/10.1104/pp.105.067371
- ↑ Ezaki B, Kiyohara H, Matsumoto H, Nakashima S. Overexpression of an auxilin-like gene (F9E10.5) can suppress Al uptake in roots of Arabidopsis. J Exp Bot. 2007;58(3):497-506. Epub 2006 Dec 5. PMID:17150990 doi:http://dx.doi.org/10.1093/jxb/erl221
- ↑ Takano A, Suetsugu N, Wada M, Kohda D. Crystallographic and functional analyses of J-domain of JAC1 essential for chloroplast photorelocation movement in Arabidopsis thaliana. Plant Cell Physiol. 2010 Aug;51(8):1372-6. Epub 2010 Jun 20. PMID:20562448 doi:10.1093/pcp/pcq089
- ↑ Ichikawa S, Yamada N, Suetsugu N, Wada M, Kadota A. Red light, Phot1 and JAC1 modulate Phot2-dependent reorganization of chloroplast actin filaments and chloroplast avoidance movement. Plant Cell Physiol. 2011 Aug;52(8):1422-32. doi: 10.1093/pcp/pcr087. Epub 2011, Jul 7. PMID:21737483 doi:http://dx.doi.org/10.1093/pcp/pcr087
- ↑ Takano A, Suetsugu N, Wada M, Kohda D. Crystallographic and functional analyses of J-domain of JAC1 essential for chloroplast photorelocation movement in Arabidopsis thaliana. Plant Cell Physiol. 2010 Aug;51(8):1372-6. Epub 2010 Jun 20. PMID:20562448 doi:10.1093/pcp/pcq089
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