Ribosomal protein S28

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Template:STRUCTURE 1ne3

Contents 1 Function 2 Relevance 3 3D Structures of Ribosomal protein S28 4 References

Function

Ribosomal protein S28 (RPS28 in eukaryotes/archaea) is one of the ca. 33 proteins which belong to the small 40S subunit of the eukaryotic ribosome. It is found also in the small 30S subunit of archaea^[1].

Relevance

Mutations in yeast RPS28 affect the accuracy of translation^[2].

3D Structures of Ribosomal protein S28

Updated on 17-August-2016

1ne3 – RPS28 – NMR – Methanobacterium thermoautotrophicum
1ny4 – RPS28 – NMR – Pyroccocus horikoshii

References

1. ↑ Wu B, Yee A, Pineda-Lucena A, Semesi A, Ramelot TA, Cort JR, Jung JW, Edwards A, Lee W, Kennedy M, Arrowsmith CH. Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum. Protein Sci. 2003 Dec;12(12):2831-7. PMID:14627743
2. ↑ Synetos D, Frantziou CP, Alksne LE. Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin. Biochim Biophys Acta. 1996 Nov 11;1309(1-2):156-66. PMID:8950190