Selenocysteine synthase

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Template:STRUCTURE 2z67

Selenocysteine synthase (SecS) converts phospho-seryl-tRNA into selenocysteinyl-tRNA using selenophosphate as the Se donor[1].

3D Structures of selenocysteine synthase

Updated on 24-August-2016

3bc8, 3bca - mSecS elastase-resistant fragment - mouse

3bcb - mSecS elastase-resistant fragment + phosphate

2z67 - SecS - Methanococcus maripaludis

3hl2 - SecS + tRNASec - human
3w1i – AaSecS + pyridine derivative – Aquifex aeolicus
3wcn – AaSecS (mutant)
3w1h, 3wco – AaSecS (mutant) + pyridine derivative
3w1j – AaSecS + pyridine derivative
3w1k – AaSecS (mutant) + pyridine derivative + tRNASec

References

  1. ↑ Forchhammer K, Boesmiller K, Bock A. The function of selenocysteine synthase and SELB in the synthesis and incorporation of selenocysteine. Biochimie. 1991 Dec;73(12):1481-6. PMID:1839607

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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