N-acetylornithine carbamoyltransferase

From Proteopedia

Revision as of 17:48, 16 January 2017 by Michal Harel (Talk | contribs)

(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)

N-acetylornithine carbamoyltransferase complex with acetylornithine (PDB code 3kzn)

Drag the structure with the mouse to rotate

or to the article describing Jmol ^[1] to the rescue.

1 Function
2 Disease
3 Relevance
4 Structural highlights

Function

N-acetylornithine carbamoyltransferase (AOCT) catalyzes the reversible conversion of carbamoyl phosphate and N-acetyl-L-ornithine into N-acetyl-L-citrulline and phosphate.

Disease

Relevance

Structural highlights

3D structures of N-acetylornithine carbamoyltransferase

3m4j - XcAOCT + acetyl-phosphonoacetyl ornithine - Xanthomonas campestris
3m4n, 3m5c, 3m5d - XcAOCT (mutant) + acetyl-phophonoacetyl ornithine
3kzc = XcAOCT
3kzm - XcAOCT + carbamylphosphate
3kzn - XcAOCT + acetyl ornithine
3kzo - XcAOCT + acetyl norvaline + carbamyl phosphate
3l02, 3l04, 3l05, 3l06 - XcAOCT (mutant) + norvaline derivative + carbamyl phosphate

References

↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644