From Proteopedia
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Function
The telomerase-associated proteins (TAP) are components of the ribonucleoprotein complex responsible for telomerase activity and catalyze the addition of new telomeres on the chromosome ends[1].
Disease
Relevance
Structural highlights
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3D structures of telomerase-associated protein
5dof, 5dfm - TtTAP 19 - Tetrahymena thermophyla
5doi - TtTAP 19 + TAP p45
5dok - TtTAP p45
5dfn - TtTAP p45 C-terminal
2lsl - TtTAP p65 C-terminal - NMR
4erd - TtTAP p65 C-terminal + RNA
4eyt - TtTAP p65 C-terminal
3u4v, 3u4z, 3u50 - TtTAP 82 TEB1 domain
References
- ↑ Lewis KA, Wuttke DS. Telomerase and telomere-associated proteins: structural insights into mechanism and evolution. Structure. 2012 Jan 11;20(1):28-39. doi: 10.1016/j.str.2011.10.017. PMID:22244753 doi:http://dx.doi.org/10.1016/j.str.2011.10.017
