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tRNA fMet

spinqualitylabelsall models This is the three-dimensional structure of the tRNA fMet molecule Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Function:

tRNA fMet is the tRNA used for the initiation of protein synthesis. It is the fist tRNA molecule that enters the ribosome, specifically at the P site, as opposed to all other tRNAs which enter the A site. The amino acid attached to tRNA fMet is N-formylmethionine, which is the first amino acid assembled into the polypeptide chain during bacterial translation. It corresponds to the start codon, "AUG." Additional amino acids then bond with the N-formylmethionine attached to tRNA fMet, in order to assemble a protein. In this way, tRNA fMet is one of the molecules that begins the process of converting genetic code to protein.