This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox Reserved 1269
From Proteopedia
|
Contents |
Function of 1YSA
1YSA is a transcription factor that activates over 30 genes necessary for amino acid or purine biosynthesis. 1YSA binds to the DNA sequence: 5'-TGA[CG]TCA-3' (1).
Structure, Interactions, and Location
1YSA is a four-chain structure. It interacts with DNA and binds DNA as a dimer. 1YSA interacts in several locations within the DNA. Additionally, 1YSA interacts with the protein Gcn4. Within DNA, 1YSA binds to DNA (5'-3 D(*tp*tp*cp*cp*tp*ap*tp*gp*ap*cp*tp*cp*ap*tp*cp*cp*a4 P*gp*tp*t)-3') and DNA (5'-9 D(*ap*ap*ap*cp*tp*gp*gp*ap*tp*gp*ap*gp*tp*cp*ap*tp*a10 P*gp*gp*a)-3') (2). The location of 1YSA within a cell is in nucleus P03069 (3).
Origin
1YSA originates from the organism Saccharomyces cerevisiae, or commonly known as baker's yeast (4).
References
(1) www.proteopedia.org/wiki/index.php/1ysa
(2) www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?uid=1ysa
(3) www.pdbj.org/mine/summary/1ysa
(4) www.uniprot.org/uniprot/P03069
