Sandbox Reserved 1066
From Proteopedia
Contents |
Zn Transporter YiiP
This is a default text for your page Kyle Colston/Sandbox 1'. Click above on edit this page' to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Organism
This protein is found in E. coli
Mechanism for Transport
Zinc Induced Conformation Change
The ligand binding domains (CTD) and pore domains (TMD) are connected by the flexible loop that houses the charge interlock mechanism that helps hold the homodimer together. This flexible loop also acts as a hinge for the CTDs to come together and bind Zn at active site C. Zn binding to the CTD causes a conformation change in the TMD which ca
Allosteric Inhibition
Zn binding to Active Site C causes a conformation change that reduces the affinity for Zn at Active Site A.
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
