Structural highlights
Function
[ISPF_BACSU] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).[1]
References
- ↑ Julsing MK, Rijpkema M, Woerdenbag HJ, Quax WJ, Kayser O. Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. Appl Microbiol Biotechnol. 2007 Jul;75(6):1377-84. Epub 2007 Apr 26. PMID:17458547 doi:http://dx.doi.org/10.1007/s00253-007-0953-5
